GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs757978 | 1 | rs3732276 | chr2:242343404 | SEPT2 | chr2:242254723-242293439:+ | 0.43 | 5.77 | 1.01E-7 | Chronic lymphocytic leukemia |
| THYM | cis | rs3772130 | 1 | rs3732408 | chr3:121421179 | IQCB1 | chr3:121488610-121553926:- | 0.45 | 4.25 | 5.03E-5 | Cognitive performance |
| THYM | cis | rs1535500 | 1 | rs3734618 | chr6:39284184 | KCNK17 | chr6:39266778-39282237:- | -0.47 | -4.73 | 7.83E-6 | Type 2 diabetes |
| THYM | cis | rs9309473 | 1 | rs3738848 | chr2:73761881 | ALMS1P | chr2:73872046-73912692:+ | 0.58 | 4.7 | 8.77E-6 | Metabolite levels |
| THYM | cis | rs7849270 | 1 | rs3739843 | chr9:131882961 | CRAT | chr9:131857075-131873070:- | 0.38 | 4.61 | 1.24E-5 | Blood metabolite ratios |
| THYM | cis | rs7849270 | 1 | rs3739847 | chr9:131911574 | CRAT | chr9:131857075-131873070:- | -0.42 | -4.98 | 2.82E-6 | Blood metabolite ratios |
| THYM | cis | rs8010715 | 1 | rs3742500 | chr14:24611978 | FAM158A | chr14:24608175-24610797:- | -0.3 | -9.36 | 3.95E-15 | IgG glycosylation |
| THYM | cis | rs4803480 | 1 | rs3745937 | chr19:42071289 | CEACAM21 | chr19:42055886-42093196:+ | 0.69 | 9.09 | 1.46E-14 | Schizophrenia |
| THYM | cis | rs12780845 | 1 | rs3752950 | chr10:17203356 | CUBN | chr10:16865966-17171816:- | 0.31 | 4.8 | 5.85E-6 | Homocysteine levels |
| THYM | cis | rs10416265 | 1 | rs3760891 | chr19:33599708 | GPATCH1 | chr19:33571786-33621318:+ | 0.37 | 4.33 | 3.69E-5 | Bone properties (heel) |
| THYM | cis | rs9976767 | 1 | rs3761378 | chr21:43832918 | TMPRSS3 | chr21:43791996-43816200:- | -0.5 | -4.73 | 7.78E-6 | Type 1 diabetes |
| THYM | cis | rs7528684 | 1 | rs3761959 | chr1:157669278 | FCRL3 | chr1:157646278-157670775:- | 0.3 | 4.26 | 4.85E-5 | Type 1 diabetes autoantibodies |
| THYM | cis | rs9457247 | 1 | rs376551 | chr6:167384923 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs376574 | chr6:167389956 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs3770752 | 1 | rs3770752 | chr2:37576136 | CEBPZ | chr2:37428778-37458740:- | 0.42 | 4.2 | 6.08E-5 | Schizophrenia |